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(p. 171) Neural Findings in Pediatric Irritability 

(p. 171) Neural Findings in Pediatric Irritability
(p. 171) Neural Findings in Pediatric Irritability

Emily Hirsch

, and Leslie Hulvershorn

Page of

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date: 15 July 2020

Irritability has been conceptualized as a clinical phenomenon that cuts across various psychiatric disorders. Moreover, it is one of the most common reasons that children and adolescents present for mental health treatment. Despite the high prevalence and impairment associated with irritability, until recently, relatively little was known about the brain mechanisms underlying it. Understanding more about the neural mechanisms associated with irritability will likely enhance treatment development. In this chapter, the authors synthesize research that has characterized aspects of irritability in children and adolescents who are typically developing and in those with psychiatric disorders, including severe mood dysregulation (SMD), disruptive mood dysregulation disorder (DMDD), bipolar disorder, and disruptive behavior disorders, as well as attention deficit/hyperactivity disorder and autism, and they suggest future directions for research in this area.

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