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- Dedication
- Acknowledgments
- Contributors
- Introduction
- 1 Animal Models of Drug Addiction
- 2 Human Laboratory Models of Addiction
- 3 Neuroanatomy of Addiction
- 4 Genetics of Addiction
- 5 Epigenetic Changes in Addiction and Eating Disorders
- 6 Feeding Systems and Drugs of Abuse
- 7 Co-Occurring Addiction and Psychiatric Disorders
- 8 The Study of Craving and Its Role in Addiction
- 9 Stress and Addiction
- 10 The Changing Face of Global Diet and Nutrition
- 11 Weight and Diet among Children and Adolescents in the United States, 2005–2008
- 12 Genetics of Body Weight Regulation
- 13 Central Regulation of Hunger, Satiety, and Body Weight
- 14 Peripheral Regulation of Hunger and Satiety
- 15 Food Intake and Metabolism
- 16 Neuroendocrine Regulation of Energy Balance
- 17 Prenatal Programming of Obesity
- 18 The Biology and Psychology of Taste
- 19 Leptin Gene Therapy for Hyperphagia, Obesity, Metabolic Diseases, and Addiction
- 20 Lessons from Prader-Willi Syndrome and Pathological Brain Reinforcement
- 21 Environmental Toxins as Triggers for Obesity
- 22 The Special Case of Sugar-Sweetened Beverages
- 23 The Impact of Portion Size and Energy Density on Eating
- 24 Specific Environmental Drivers of Eating
- 25 Food Addiction and Diagnostic Criteria for Dependence
- 26 Phylogenetic and Ontogenetic Contributions to Today’s Obesity Quagmire
- 27 Food Reward
- 28 Dopamine Deficiency, Eating, and Body Weight
- 29 Genes and Reward Circuitry as Predictors of Eating and Weight Gain
- 30 Hormones, Hunger, and Food Addiction
- 31 Bingeing, Withdrawal, and Craving
- 32 Incubation of Sucrose Craving in Animal Models
- 33 Liking versus Wanting Food in Human Appetite
- 34 The Psychology of Food Cravings
- 35 Is Sugar as Addictive as Cocaine?
- 36 Caffeine, Addiction, and Food Consumption
- 37 Interactions between Smoking, Eating, and Body Weight
- 38 Interactions between Alcohol Consumption, Eating, and Weight
- 39 Relationships between Drugs of Abuse and Eating
- 40 Stress and Reward
- 41 Public Attitudes about Addiction as a Cause of Obesity
- 42 Clinical Assessment of Food and Addiction
- 43 Psychological Treatments for Substance Use Disorders
- 44 Behavioral Treatments for Obesity
- 45 Pharmacotherapy of Addictive Disorders
- 46 Pharmacotherapy for Obesity
- 47 Surgical Treatments for Obesity
- 48 Treatment of Alcohol and Drug Dependence in 2011 and Relevance to Food Addiction
- 49 Treatment of Binge Eating Disorder
- 50 Exercise Addiction and Aversion
- 51 New Treatments for Obesity Based on Addiction Models
- 52 From the Front Lines
- 53 From the Front Lines
- 54 Food and Addiction
- 55 Taxes on Energy-Dense Foods to Improve Nutrition and Prevent Obesity
- 56 Addressing Disparities Related to Food Intake and Obesity
- 57 Is Food Advertising Feeding Americans’ Sugar Habit?
- 58 Environmental Interventions to Reduce Overeating in Children
- 59 Nutrition Practices in Schools
- 60 Legal and Policy Implications
- 61 Legal Implications
- 62 What Lessons for Food Policy Can Be Learned from Alcohol Control?
- 63 Policy Lessons Learned from Tobacco
- 64 Lessons from Drug Policy
- 65 Global Policies Affecting Diet and Obesity
- 66 Food and Addiction
- Index
(p. 90) Genetics of Body Weight Regulation
(p. 90)
Genetics of Body Weight Regulation
- Chapter:
- (p. 90) Genetics of Body Weight Regulation
- Author(s):
Wendy K. Chung
and Rudolph L. Leibel
- DOI:
- 10.1093/med:psych/9780199738168.003.0012
Chapter 12 discusses the genetics of body weight regulation, including classical linkage analysis, candidate gene association studies, direct analysis of candidate genes, genome-wide association, copy number variants, and other considerations.
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- Dedication
- Acknowledgments
- Contributors
- Introduction
- 1 Animal Models of Drug Addiction
- 2 Human Laboratory Models of Addiction
- 3 Neuroanatomy of Addiction
- 4 Genetics of Addiction
- 5 Epigenetic Changes in Addiction and Eating Disorders
- 6 Feeding Systems and Drugs of Abuse
- 7 Co-Occurring Addiction and Psychiatric Disorders
- 8 The Study of Craving and Its Role in Addiction
- 9 Stress and Addiction
- 10 The Changing Face of Global Diet and Nutrition
- 11 Weight and Diet among Children and Adolescents in the United States, 2005–2008
- 12 Genetics of Body Weight Regulation
- 13 Central Regulation of Hunger, Satiety, and Body Weight
- 14 Peripheral Regulation of Hunger and Satiety
- 15 Food Intake and Metabolism
- 16 Neuroendocrine Regulation of Energy Balance
- 17 Prenatal Programming of Obesity
- 18 The Biology and Psychology of Taste
- 19 Leptin Gene Therapy for Hyperphagia, Obesity, Metabolic Diseases, and Addiction
- 20 Lessons from Prader-Willi Syndrome and Pathological Brain Reinforcement
- 21 Environmental Toxins as Triggers for Obesity
- 22 The Special Case of Sugar-Sweetened Beverages
- 23 The Impact of Portion Size and Energy Density on Eating
- 24 Specific Environmental Drivers of Eating
- 25 Food Addiction and Diagnostic Criteria for Dependence
- 26 Phylogenetic and Ontogenetic Contributions to Today’s Obesity Quagmire
- 27 Food Reward
- 28 Dopamine Deficiency, Eating, and Body Weight
- 29 Genes and Reward Circuitry as Predictors of Eating and Weight Gain
- 30 Hormones, Hunger, and Food Addiction
- 31 Bingeing, Withdrawal, and Craving
- 32 Incubation of Sucrose Craving in Animal Models
- 33 Liking versus Wanting Food in Human Appetite
- 34 The Psychology of Food Cravings
- 35 Is Sugar as Addictive as Cocaine?
- 36 Caffeine, Addiction, and Food Consumption
- 37 Interactions between Smoking, Eating, and Body Weight
- 38 Interactions between Alcohol Consumption, Eating, and Weight
- 39 Relationships between Drugs of Abuse and Eating
- 40 Stress and Reward
- 41 Public Attitudes about Addiction as a Cause of Obesity
- 42 Clinical Assessment of Food and Addiction
- 43 Psychological Treatments for Substance Use Disorders
- 44 Behavioral Treatments for Obesity
- 45 Pharmacotherapy of Addictive Disorders
- 46 Pharmacotherapy for Obesity
- 47 Surgical Treatments for Obesity
- 48 Treatment of Alcohol and Drug Dependence in 2011 and Relevance to Food Addiction
- 49 Treatment of Binge Eating Disorder
- 50 Exercise Addiction and Aversion
- 51 New Treatments for Obesity Based on Addiction Models
- 52 From the Front Lines
- 53 From the Front Lines
- 54 Food and Addiction
- 55 Taxes on Energy-Dense Foods to Improve Nutrition and Prevent Obesity
- 56 Addressing Disparities Related to Food Intake and Obesity
- 57 Is Food Advertising Feeding Americans’ Sugar Habit?
- 58 Environmental Interventions to Reduce Overeating in Children
- 59 Nutrition Practices in Schools
- 60 Legal and Policy Implications
- 61 Legal Implications
- 62 What Lessons for Food Policy Can Be Learned from Alcohol Control?
- 63 Policy Lessons Learned from Tobacco
- 64 Lessons from Drug Policy
- 65 Global Policies Affecting Diet and Obesity
- 66 Food and Addiction
- Index
